Position Details Position Information Recruitment/Posting Title Postdoctoral Associate in Structural Virology Department Proteomics Salary Commensurate With Experience Posting Summary The Kaelber lab is recruiting a scientist to work on the boundaries of structural biology and virology, using cryo-electron microscopy to answer fundamental questions in viral gene delivery and infection of mammalian cells, and to contribute toward structure-based rational design of viral nanotechnologies such as gene therapy vectors. This position will involve significant collaborations with scientists in academia and industry. Training will be provided in cutting-edge cryogenic ultramicroscopy technologies including cryoFIB. Mentorship of 1-2 undergraduate students will be encouraged. The proposed experimental portfolio is balanced with both low-risk and high-risk experiments. BSL-2 pathogens will be utilized. Areas of specific focus include adeno-associated virus and other mammalian parvoviruses. The candidate will culture and infect cells with recombinant virions and leverage in situ nanoimaging techniques to understand the molecular mechanisms of nuclear entry and uncoating. The Kaelber lab is located in the Institute for Quantitative Biomedicine, home to several experts in cryoEM and in molecular dynamics. The building is shared with the RCSB Protein Data Bank (PDB). Prof. Kaelber also directs the Rutgers New Jersey Cryo-electron Microscopy & Tomography Core Facility, which contains four electron microscopes including North America's first "Aquilos 2"-model cryogenic focused ion beam/scanning electron microscope as well as a Krios cryoTEM. Position Status Full Time Posting Number 24FA0858 Posting Open Date 09/03/2024 Posting Close Date Qualifications Minimum Education and Experience Terminal degree in life sciences or chemical sciences. Exceptional candidates with 5+ years' relevant research experience may also be considered at the Research Assistant level. Certifications/Licenses Required Knowledge, Skills, and Abilities At least one of the following is required, but more are preferred: * Excellence in classical and molecular virology * Excellence in biochemistry * Excellence in cryoelectron tomography * Excellence in structural bioinformatics Additionally required skills are: * Commitment to ethical conduct of research * Self-motivation and independence * Good documentation habits * Proficiency with Unix command line * A track record of productive, "wet-lab" results Equipment Utilized Cryo-transmission electron microscope; cryo-focused ion beam; cryo-scanning electron microscope; cryo-fluorescence microscope; biosafety cabinet; ultracentrifuge; plate reader; vitrification robot Physical Demands and Work Environment Experiments require fine manual dexterity for manipulation of small objects under cryogenic conditions, and vision in low light conditions. Overview Statement Posting Details Special Instructions to Applicants Applicants should provide a cover letter relating their research and career interests to this position, a full curriculum vitae, and names and contact information for three references. Applications will be reviewed on a rolling basis until the position is filled. Must be willing to start by 1 December 2024. Quick Link to Posting https://jobs.rutgers.edu/postings/234919 Campus Rutgers University-New Brunswick Home Location Campus Busch (RU-New Brunswick) City Piscataway State NJ Location Details Pre-employment Screenings All offers of employment are contingent upon successful completion of all pre-employment screenings. Immunization Requirements Under Policy 100.3.1 Immunization Policy for Covered Individuals, if employment will commence during Flu Season, Rutgers University may require certain prospective employees to provide proof that they are vaccinated against Seasonal Influenza for the current Flu Season, unless the University has granted the individual a medical or religious exemption. Additional infection control and safety policies may apply. Prospective employees should speak with their hiring manager to determine which policies apply to the role or position for which they are applying. Failure to provide proof of vaccination for any required vaccines or obtain a medical or religious exemption from the University will result in rescission of a candidate's offer of employment or disciplinary action up to and including termination. 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For additional information please see the Non-Discrimination Statement at the following web address: http://uhr.rutgers.edu/non-discrimination-statement Posting Specific Questions Required fields are indicated with an asterisk (*). Applicant Documents Required Documents * Resume/CV * Cover Letter/Letter of Application Optional Documents * Transcript (Unofficial) * Research Statement