Research Investigator/Sr. Research Investigator/Associate Director, Clinical Pharmacology and Pharmacometrics

Is this the role you are looking for If so read on for more details, and make sure to apply today. Working with Us Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

The Clinical Pharmacology and Pharmacometrics (CP&P) team at BMS is responsible for the pharmacology and pharmacometric support for all pipeline assets throughout the clinical development lifecycle. Composed of pharmacologists, pharmacometricians, data scientists and modelers, this group oversees the pharmacokinetic evaluation, pharmacometric exposure-response evaluation, quantitative systems pharmacology modeling, physiologically based pharmacokinetic modeling and model based meta-analysis of assets covering all therapeutic modalities, including small molecules, traditional and complex biologics and next gen cell therapies. All therapeutic areas are supported.

The CP&P team interacts with discovery and translational scientists, project leadership, early and late clinical development teams and commercial colleagues to provide input on clinical pharmacology profiling, dose optimization, formulation bridging, and combination strategies to enable faster and more effective drug development informed by core scientific principles and data.

Responsibilities

Independently contribute

to compound development across various development phases

Represent

Clin Pharm on asset teams and at governance meetings based on proficiency

Provide input

to Phase 2/3 clinical study design and registrational strategy

Accountable for the

Clinical Pharmacology Plan

Lead

design of clinical pharmacology studies and manages data analysis, interpretation, and reporting

High proficiency

in PK, PK/PD, and model informed drug development (MIDD) principles and analyses

Collaborate

on cross-functional drug development teams, and regulatory submissions; serves as Clinical Pharmacology subject matter expert

Lead and participate

in departmental initiatives and represent CP&P on cross-functional initiatives / workstreams / taskforces

Participate

in interactions with health authorities; serves as Clinical Pharmacology subject matter expert

Provide

critical expertise to Business Development teams to assess external acquisitions

Requirements

Advanced Degree in related field (MS, Ph.D. or PharmD)

For Associate Director level with Ph.D. approximately 5+ years experience with demonstrated progression clinical pharmacology and Pharmacometrics experience

For Sr. Research Investigator, with Ph.D. approximately 2+ years experience with demonstrated progression clinical pharmacology and Pharmacometrics

For Research Investigator, with Ph.D. approximately 0-2 years experience with demonstrated progression clinical pharmacology and Pharmacometrics

Demonstrated ability to work in a dynamic team-oriented environment

Expertise in general drug development

Expertise in small molecule and/or biologic drug property characterization

Demonstrated stakeholder management with strong influence/leadership

Quantitative data analysis, POP PK/PD, and data visualization skills

Programming experience (e.g., NONMEN, Phoenix NLME, Monolix, R, WinNonlin, SAS, Splus etc.)

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If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as “Transforming patients’ lives through science”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

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