Job Title Postdoctoral Research Associate Agency Texas A&M University Health Science Center Department Cell Biology and Genetics Proposed Minimum Salary Commensurate Job Location College Station, Texas Job Type Staff Job Description Our Commitment Texas A&M University is committed to enriching the learning and working environment by promoting a culture that respects all perspectives, talents & lived experiences. Embracing varying opinions and perspectives strengthens our core values which are: Respect, Excellence, Leadership, Loyalty, Integrity, and Selfless Service. Who we are As one of the fastest-growing academic health centers in the nation, Texas A&M Health encompasses five colleges and numerous centers and institutes working together to improve health through transformative education, innovative research and team-based health care delivery. What we want The Postdoctoral Research Associate is responsible is to use 3D single particle tracking methods and super-resolution fluorescence microscopy to decipher structural and function properties of nuclear pore complexes. This is a demanding project that requires considerable technical and analytical expertise. The work continues a long-standing project building on recent breakthroughs in rapid multi-color 3D imaging. Structural and dynamical aspects of the nuclear pore permeability barrier and cargo trafficking pathways will be resolved with high spatial (< 10 nm) and millisecond-scale resolution. What you need to know Other Requirements and Factors: Ability to work beyond normal office hours and/or on weekends as needed. Ability to travel to various locations. Required Education: * PhD in Biophysics, Quantitative Biosciences, or other relevant field Required Knowledge, Skills, and Abilities: * Ability to develop novel light microscopy methods. * Highly motivated and able to work independently. * Ability to multitask and work cooperatively with others. Preferred Qualifications: * A strong background and training in quantitative biology and light microscopy. * Experience and/or interest in single molecule fluorescence microscopy, particle tracking, image analysis, and nucleocytoplasmic transport. * Ability to communicate effectively both orally and through writing. * MATLAB programming ability, and a strong skillset/background in biochemical and biophysical methods and approaches. Responsibilities: * Single Molecule and Super-Resolution Fluorescence Microscopy Experiments: Designing, planning, and implementing 3D super-resolution fluorescence microscopy experiments to decipher structural and functional properties of nuclear pore complexes. * Data Analysis: Use existing algorithms and design new approaches to analyze microscopy data in order to understand its implications for understanding nucleocytoplasmic transport. Analyzed data will be reported at conferences and within research publications and may be used in future grant proposals. * Protein Modification, Purification and Dye Labeling: Mutagenesis, purification and labeling of nuclear transport substrates and nuclear transport cofactors. Ability to operate a fluorescence microscope in the dark. Instructions to Applicants: Applications received by Texas A&M University must either have all job application data entered or a resume attached. Failure to provide all job application data or a complete resume could result in an invalid submission and a rejected application. We encourage all applicants to upload a resume or use a LinkedIn profile to pre-populate the online application. All positions are security-sensitive. Applicants are subject to a criminal history investigation, and employment is contingent upon the institution's verification of credentials and/or other information required by the institution's procedures, including the completion of the criminal history check. Equal Opportunity/Affirmative Action/Veterans/Disability Employer.