For Current Gilead Employees and Contractors: Please log onto your Internal Career Site to apply for this job. At Gilead, we're creating a healthier world for all people. For more than 35 years, we've tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer - working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world's biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead's team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we're looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description We are seeking a highly motivated Research Scientist to join our Inflammation in vivo group at Gilead Sciences. The candidate will be responsible for daily execution of in vivo pharmacological studies to support pipeline and research advancement associated with autoimmune and inflammatory diseases, such as IBD, arthritis, and fibrotic diseases. Hands-on experience and substantiated knowledge with preclinical models of inflammatory and autoimmune diseases is required. The successful candidate will be responsible for designing, generating and communicating pharmacology data of preclinical models internally to support inflammatory target discovery for autoimmunity. A successful candidate should be highly proficient in routine murine handling techniques including but not limited to IV, IP, PO, SC, retro-orbital bleed, and terminal cardiac sticks. Harvesting and processing tissues for ex vivo analysis is also required. The ideal candidate is able to independently execute in vivo studies from start to finish and can contribute to new model development to support our programs. A strong collaborative spirit and great communication skills are needed to be successful in this role. The candidate should be detail-oriented and highly organized to cope with the multi-tasking environment. The candidate will be willing to learn and grow both in technical skills and knowledge basis to adapt to the dynamic character of industry research. Primary responsibilities: * Designing, conducting, analyzing and reporting in vivo studies (efficacy, PK/PD) * Pre-clinical model development, optimization, and characterization * Interface with cross-functional project team members, and participation in and presentation at project team meetings and cross-departmental team meetings Qualifications & prior experience: * Bachelor's or master's degree with 12+ years of industry experience in in vivo pharmacology with a solid understanding of inflammatory disease pathogenesis preferred * Hands-on experience in mouse models of inflammation such as collagen induced arthritis, Ovalbumin induced asthma, experimental colitis, and various fibrotic models (Bleomycin, CCl4 etc). Experience with bacterial infection models and humanized mice is a plus. * Proficiency with various mouse handling techniques including dosing (IV, PO, SC, IP), preclinical manifestation scoring (e.g., joint swelling, paralysis), and collection and handling of tissues during necropsy and processing for ex vivo analysis * Excellent organizational and communication skills, along with the ability to work effectively in a multidisciplinary team environment * The ability to work independently on day-to-day responsibilities and research goals as well as in a team-oriented environment * Familiarity with cellular, biochemical, histological and molecular biology assay techniques such as ELISA, flow cytometry and qPCR is preferred The salary range for this position is: $143,225.00 - $185,350.00. Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*. For additional benefits information, visit: https://www.gilead.com/careers/compensation-benefits-and-wellbeing * Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans. For jobs in the United States: As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact ApplicantAccommodations@gilead.com for assistance. For more information about equal employment opportunity protections, please view the 'Know Your Rights' poster. NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT PAY TRANSPARENCY NONDISCRIMINATION PROVISION Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team. Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion. For Current Gilead Employees and Contractors: Please log onto your Internal Career Site to apply for this job.