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POSITION SUMMARY The Webb Lab at the Buck Institute is recruiting a Postdoctoral Scientist to investigate the molecular mechanisms of brain aging and neurodegeneration. The successful candidate will have experience in molecular biology and/or neuroscience. A strong bioinformatics or data science background is desirable but not required. Candidates should have a track record of contribution to peer-reviewed publications, innovative problem-solving skills, and the ability to work well with a team. The Webb Lab investigates the molecular mechanisms of brain aging and neurodegeneration, with a focus on transcriptional and epigenetic mechanisms. We use a combination of cell-based models, in vivo mouse models, and genomics to interrogate age-related changes and identify new targets to treat age-related cognitive decline and neurodegeneration. The Webb Lab is an inclusive environment, and we welcome individuals from all backgrounds and identities. KEY RESPONSIBILITIES * Design and perform experiments to interrogate the mechanisms of neuronal aging and cognitive decline. * Use mouse models and/or cell-based systems to measure molecular features of aging and manipulate candidate targets. * Analyze data and prepare manuscripts in collaboration with the PI. * Participate in Institute events including symposia, seminars, and workshops. QUALIFICATIONS Education * PhD in Molecular Biology, Neuroscience, or a related field Experience * Cell culture and/or in vivo mouse experience * Basic molecular biology * Bioinformatics skills and experience handling high-throughput sequencing datasets is desirable but not required * Attention to detail and the ability to work independently * Collaborative and inclusive approach to science ABOUT US Our success will ultimately change healthcare. At the Buck, we aim to end the threat of age-related diseases for this and future generations by bringing together the most capable and passionate scientists from a broad range of disciplines to identify and impede the ways in which we age. We are an independent, non-profit institution located in Marin County, CA, with the goal of increasing human healthspan, or the healthy years of life. Globally recognized as the pioneer and leader in efforts to target aging-the number one risk factor for diseases including Alzheimer's, Parkinson's, cancer, macular degeneration, heart disease, and diabetes-the Buck seeks to help people live better longer. We are an equal-opportunity employer and strive to create an atmosphere where diversity of identity, experience, and background are welcomed, valued, and supported. Candidates who contribute to this diversity are strongly encouraged to apply. COMPENSATION & BENEFITS * The starting salary for a new postdoc at the Buck is $70,000 in 2024, with a range up to $82,000 commensurate with postdoc level & experience. * Exciting, dynamic work environment at the forefront of science using state-of-the-art techniques. * Generous benefits package including health insurance, paid parental leave, generous PTO and 401(k) with 5% employer match and profit sharing. * Collaborative environment - both for science and social activities. TO APPLY Apply online by uploading a CV and Cover Letter that describes your research experience and interests, as well as contact information for three references. For more information, please contact: Ashley Webb, PhD, [email protected]

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